Polygonum Cuspidatum Extract

What is Polygonum Cuspidatum Extract? 

• Plant Source: It is derived from the root and rhizome of the Japanese knotweed (Polygonum cuspidatum), a plant in the Polygonaceae family. Japanese knotweed has a long history of use in Traditional Chinese Medicine (TCM), often employed to promote blood circulation, clear heat, remove dampness, relieve cough, and reduce phlegm.

• Key Active Components: The significance of Polygonum cuspidatum extract lies in its role as one of the richest and most important natural sources of resveratrol and emodin. Additionally, it contains a high concentration of polyphenols.

Applications:

1. Potent Antioxidant (Core Benefit)

• Mechanism: Resveratrol and polyphenols are powerful antioxidants that effectively neutralize free radicals in the body, reducing oxidative stress and cellular damage.

• Applications:

  • Skincare: Protects skin cells from oxidative damage caused by UV radiation and environmental pollution, thereby delaying skin aging and reducing wrinkles and spots.

  • Health Supplements: Supports cardiovascular and nervous system health and protects overall cellular health by combating aging.

2. Anti-Inflammatory Effects

• Mechanism: Both resveratrol and emodin inhibit the production of various pro-inflammatory factors (such as TNF-α and IL-6), thereby reducing inflammatory responses.

• Applications:

  • Health Supplements: Helps alleviate inflammation-related conditions such as arthritis and atherosclerosis (which is itself a chronic inflammatory condition).

  • Skincare: Soothes sensitive, red, or acne-prone skin.

3. Skin Protection and Anti-Aging

• Mechanism:

  • Inhibits Melanin Production: Studies show that Polygonum cuspidatum extract can inhibit tyrosinase activity, a key enzyme in the melanin production process, making it effective for brightening and whitening the skin.

  • Promotes Collagen Production: Through its antioxidant effects, it protects fibroblasts and helps maintain the structure of collagen and elastin, preserving skin elasticity.

  • Anti-Photoaging: Protects the skin from UV damage.

• Applications: Widely used in anti-aging serums, whitening creams, sunscreens, and reparative products.

4. Promotes Cardiovascular Health

• Mechanism: Resveratrol helps reduce blood viscosity, inhibit platelet aggregation, improve endothelial function (vasodilation capacity), and prevent the oxidation of “bad” cholesterol (LDL), which is beneficial for preventing atherosclerosis.

• Applications: Commonly found in dietary supplements for cardiovascular health.

5. Other Potential Benefits

• Neuroprotective Effects: Its antioxidant and anti-inflammatory properties may offer potential protective effects against neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

• Metabolic Regulation: Some studies have explored its role in regulating blood sugar and lipid levels.

• Antimicrobial and Antiviral Properties: Emodin exhibits certain antibacterial and antiviral activities.

Fuctions:

1. Skincare Products:

   • Used as a functional additive in anti-aging, antioxidant, brightening, and anti-inflammatory products.

   • Commonly found in serums, creams, lotions, and masks.

2. Dietary Supplements/Health Products:

   • Encapsulated or tableted for antioxidant support, anti-aging, cardiovascular health, and anti-inflammatory purposes.

   • Often labeled as “resveratrol supplements,” with many sourced from Polygonum cuspidatum extract.

3. Traditional Medicine:

   • Used in combination with other herbs under the guidance of TCM principles.

💎Polygonum Cuspidatum Extract COA generally includes the following test items and standards:

TEST ITEM	SPECIFICATION	TEST RESULT	TEST METHOD
Identification	Complies with structure	Complies	USP/In-house
Appearance	White or almost white powder	White powder	Visual
Assay (HPLC)	98.0% - 101.0% (on dried basis)	99.5%	USP/In-house
Loss on Drying	≤ 0.5%	0.2%	USP/In-house
Residue on Ignition	≤ 0.1%	0.05%	USP/In-house
Heavy Metals (as Pb)	≤ 10 ppm	< 10 ppm	ICP-MS
Arsenic (As)	≤ 2 ppm	< 2 ppm	ICP-MS
Lead (Pb)	≤ 3 ppm	< 3 ppm	ICP-MS
Cadmium (Cd)	≤ 1 ppm	< 1 ppm	ICP-MS
Mercury (Hg)	≤ 1 ppm	< 1 ppm	ICP-MS
Total Plate Count	≤ 1000 CFU/g	50 CFU/g	USP/In-house
Yeast & Molds	≤ 100 CFU/g	< 10 CFU/g	USP/In-house
E. coli	Negative / 10g	Negative	USP/In-house
Salmonella	Negative / 10g	Negative	USP/In-house

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship