ll-37

What is ll-37?

LL-37, Like all Cathelicidins, has antimicrobial, antibacterial, antiviral, anti-fungal and has been shown to reduce inflammation. Research has also shows that its effect against certain cancers and encourages blood vessel growth in specific settings.

Antimicrobial peptide LL-37, belonging to the cathelicidin family, is the first amphipathic alpha-helical peptide isolated from human. It plays an important role in the first line of defense against local infection and systemic invasion of pathogens at sites of inflammation and wounds. Cytotoxic to both bacterial and normal eukaryotic cells , LL-37 is significantly resistant to proteolytic degradation in solution.

Applications:

• Antimicrobial Action: Kills Gram± bacteria and fungi by membrane pore formation; disrupts biofilms.
• Antiviral Protection: Blocks SARS-CoV-2 binding to ACE2 and disrupts viral envelopes48.
• Immunomodulation: Balances inflammation via TLR4/NF-κB pathway; enhances NET clearance28.
• Barrier Repair: Upregulates keratinocyte migration and suppresses serine protease in rosacea.

Fuctions:

• Acne Care: Serums/cleansers (0.001-0.01%) to reduce biofilm and redness12.

• Sensitive Skin: Combines with thermal water/diatom algae (e.g., Aquammunist®) to soothe irritation14.

• Whitening Enhancer: Synergizes with tranexamic acid to inhibit melanin transfer.

 💎ll-37 COA generally includes the following test items and standards:

Test Item	Specification	Result
Solution Clarity & Color	Clear and colorless	Complies
Ammonium Salt Residue	≤0.05%	Complies
Phosphate Residue	≤0.1%	Complies
Loss on Drying	≤6.0%	Complies
Single Impurity	≤0.3%	0.01%
Total Impurities	≤0.5%	0.10%
Heavy Metals	≤20 ppm	Complies
Assay (Content)	98.0%-101.0%	99.46%

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship