J-147

What is J-147 ? 

J-147 is a phenyl hydrazide compound known for its neuroprotective and neurotrophic properties. It is currently being developed in preclinical research as a potential therapeutic agent to combat cognitive decline and neurodegeneration associated with conditions like Alzheimer’s disease. Its unique mechanism of action focuses on optimizing cellular energy metabolism and protecting the brain from age-related damage.

J-147 is a novel neuroactive compound derived from structural optimization of curcumin. It is widely recognized for its potential roles in neuroprotection, anti-aging, and cognitive enhancement. As one of the most researched next-generation nootropic candidates, J-147 has attracted significant attention in the field of brain health and neurodegenerative disorder studies.

It is especially valued for its potential to improve memory, protect neurons, and enhance brain metabolism.

Applications:

Neuroprotection & Cognitive Enhancement

Protects neurons from various toxic insults; reduces levels of Alzheimer’s-associated Aβ peptides, increases hippocampal Brain-Derived Neurotrophic Factor (BDNF), and enhances memory while reversing cognitive deficits in animal models.

High-end nootropic dietary supplements, cognitive health support products.

Anti-Aging & Metabolic Modulation

Targets mitochondrial ATP synthase to regulate cellular energy metabolism. Studies show it activates the AMPK/ACC1 signaling pathway in the liver, reducing plasma free fatty acid levels, contributing to anti-aging effects at a metabolic level.

Anti-aging formulations, metabolic health supplements.

Antioxidant & Anti-inflammatory

Exerts effects by reducing oxidative stress and inflammation in the brain, key contributors to neurodegenerative diseases.

Neuroprotective health products, anti-aging ingredient in high-end skincare.

Fuctions:

• Enhances Memory & Learning
  Supports memory formation and improves learning performance.

• Neuroprotective Effects
  Helps reduce oxidative stress and inflammation, protecting neural cells.

• Anti-Aging & Metabolic Support
  May improve mitochondrial function and energy metabolism in the brain.

• Cognitive & Mood Support
  Helps maintain mental clarity and reduce cognitive fatigue.

• Premium nootropic supplements

• Brain health formulations

• Anti-aging nutritional products

• Neuroprotective product blends

• Scientific and research purposes (R&D)

 💎 CJ-147 COA  generally includes the following test items and standards:

Items	Standards	Results
Physical Analysis
Description	White Powder	Complies
Assay	99%	99.2%
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.85%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1 mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship