Tieneptine Sulphate

What is Tieneptine Sulphate ? 

Product Name: Tianeptine Sulfate (also known as Tianeptine Sulphate)
CAS Number: 1224690-84-9
Molecular Formula: C42H56Cl2N4O14S3
Appearance: Crystalline powder. The provided color information is inconsistent, with one source describing it as pale yellow, while a listing for a similar compound (Tianeptine Sodium) lists white to tan.
Melting Point: 221-223 °C
Solubility: Moderately soluble in water and methanol

Tianeptine Sulphate is a stable, sulfate-bound form of Tianeptine, commonly used as a raw material in the nutraceutical, research, and pharmaceutical ingredient markets. Compared to Tianeptine Sodium, the sulfate form offers improved stability, slower release, and better moisture resistance, making it suitable for formulation development and long-term storage.
It is intended strictly for laboratory research, formulation testing, and raw material supply.

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Applications:

Tianeptine Sulfate is the sulfate salt form of Tianeptine, an atypical tricyclic compound. Its primary mechanisms are distinct from most common antidepressants:

• Glutamate Modulation: Modern research indicates its primary antidepressant effect works by modulating and stabilizing glutamate signaling in the brain, rather than through the serotonin system.

• Opioid Receptor Activity: It acts as a full agonist of the mu-opioid receptor and a weak delta-opioid receptor agonist. This is responsible for both its potential analgesic effects and its significant risk of misuse and dependence.

Based on the pharmacological profile of Tianeptine, its sulfate salt is associated with research and potential applications in the following areas:

• Major Depressive Disorder (MDD)

• Anxiety disorders

• Post-Traumatic Stress Disorder (PTSD)

• Chronic pain conditions

• Irritable Bowel Syndrome (IBS)

• Used as a raw material in R&D for nootropic and neuro-support formulations

• Suitable for laboratory studies in cognitive and mood-related research fields

• Ideal for testing in capsule, powder, and advanced nutritional formulations

• Preferred in product development requiring long-term stability and slower release

• Commonly used by research institutions and formulation laboratories

Fuctions:

• Used in research on mood-support mechanisms
  Frequently studied for its interaction with glutamatergic pathways and neuroplasticity mechanisms.

• Applied in formulation studies for cognitive and mood-related products
  Tianeptine Sulphate is often evaluated in R&D settings for its potential use in advanced nootropic or neuro-support formulations.

• Higher stability for product development
  The sulfate form shows slower degradation and reduced hygroscopicity, making it preferred for encapsulation and powder blends.

• Suitable for long-term storage and transportation
  Its solid stability profile is helpful for global raw-material distribution in the nutraceutical and research industries.

💎 Tieneptine Sulphate  COA  generally includes the following test items and standards:

tem	Specification	Result
Appearance	White to off-white crystalline powder	Complies
Identification	Positive (HPLC/IR)	Complies
Assay (HPLC)	≥ 99.0%	99.3%
Sulphate Content	Conforms to standard	Complies
Specific Rotation	+XX° to +XX°	+XX°
Loss on Drying	≤ 1.0%	0.28%
Residue on Ignition	≤ 0.1%	0.02%
pH (1% solution)	XX – XX	XX
Heavy Metals	≤ 10 ppm	< 10 ppm
Lead (Pb)	≤ 2 ppm	< 2 ppm
Arsenic (As)	≤ 1 ppm	< 1 ppm
Mercury (Hg)	≤ 0.1 ppm	< 0.1 ppm
Cadmium (Cd)	≤ 1 ppm	< 1 ppm
Microbial Limits
Total Plate Count	≤ 1,000 cfu/g	< 100 cfu/g
Yeast & Mold	≤ 100 cfu/g	< 10 cfu/g
E. coli	Negative	Negative
Salmonella	Negative	Negative
Particle Size	95% pass 80 mesh (or customer standard)	Complies

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship