Genistein Powder

What is Genistein Powder? 

Genistein 98% is a highly purified, plant-derived isoflavone extracted primarily from soybeans (Glycine max) or other legumes like kudzu. The “98%” denotes its purity level, meaning it consists of a minimum of 98% genistein compounds, with the remaining 2% typically being other related isoflavones, moisture, and residual solvents. This high purity is essential for pharmaceutical, nutraceutical, and cosmetic applications where standardized potency and consistent efficacy are critical.

Chemically, it is classified as a phytoestrogen due to its structural similarity to the human hormone estrogen, allowing it to bind to estrogen receptors in the body. It is a fine, off-white to yellow crystalline powder with low solubility in water.

Applications:

• Potent Antioxidant: Neutralizes free radicals, reducing oxidative stress and cellular damage linked to aging and chronic diseases.

• Phytoestrogenic Activity: Modulates estrogenic effects in the body. It can act as a weak estrogen or block stronger natural estrogens, helping to maintain hormonal balance.

• Anti-Inflammatory: Inhibits key enzymes and pathways (like NF-κB and COX-2) that drive inflammation.

• Supports Bone Health: Helps reduce bone loss and promotes bone formation by influencing osteoblasts and osteoclasts, making it crucial for managing post-menopausal osteoporosis.

• Cardiovascular Support: May improve vascular elasticity and help maintain healthy cholesterol levels by reducing LDL (“bad” cholesterol) oxidation.

• Cellular Health and Apoptosis: Influences cell cycle progression and can induce apoptosis (programmed cell death) in certain abnormal cells, a key area of scientific interest.

• Enzyme Inhibition: Acts as a specific inhibitor of tyrosine kinase, an enzyme involved in cellular signaling pathways for growth and proliferation.

Fuctions:

A. Nutraceutical and Dietary Supplements:

• Women’s Health Formulas: The most common application. Used in supplements for alleviating menopausal symptoms (like hot flashes and night sweats), supporting hormonal balance, and preventing post-menopausal osteoporosis.

• General Wellness Supplements: Incorporated into capsules, tablets, and powders for its antioxidant and anti-aging benefits.

• Bone & Joint Health Formulas: Combined with calcium, vitamin D, and other minerals to enhance bone density support.

• Cardiovascular Health Supplements: Used in formulas aimed at promoting heart and vascular health.

B. Cosmetic and Personal Care Ingredients:

• Anti-Aging Creams & Serums: Its potent antioxidant activity helps protect the skin from environmental damage and reduce the appearance of wrinkles.

• Skin Brightening Products: Helps inhibit melanin production, contributing to a more even skin tone and reduction of dark spots.

• Hair Care Products: Incorporated into shampoos and treatments to promote hair health, potentially combatting hair loss related to hormonal factors.

C. Pharmaceutical Research:

• Used as a reference standard in laboratory testing and quality control.

• Serves as an active pharmaceutical ingredient (API) in clinical research and drug development for various conditions.

 💎 Genistein Powder generally includes the following test items and standards:

Parameter	Specification	Test Result	Method
Appearance	Light yellow to off-white fine powder	Complies	Visual
Odor	Characteristic	Complies	Olfactory
Mesh Size	100% through 80 mesh	Complies	Sieve Analysis
Melting Point	297℃ - 298℃	Complies	USP
Solubility	Soluble in DMSO, ethanol; almost insoluble in water	Complies	USP <
dentification	Complies with Reference Standard	Complies	HPLC , TLC/UV
Genistein Purity	≥ 98.0%	99.2%	HPLC
Water (Loss on Drying)	≤ 1.0% - 6.0%	0.5%	USP
Total Ash	≤ 1.0%	0.3%	USP
∙ Lead (Pb)	≤ 3 ppm	<1 ppm	ICP-MS
∙ Arsenic (As)	≤ 2 ppm	<0.5 ppm	ICP-MS
∙ Cadmium (Cd)	≤ 1 ppm	<0.1 ppm	ICP-MS
∙ Mercury (Hg)	≤ 0.1 ppm	<0.05 ppm	ICP-MS
Solvent Residues	Meets Eur. Ph. 7.0 24	Complies	GC
Total Plate Count	≤ 1000 CFU/g	< 100 CFU/g	USP
Yeast & Mold	≤ 100 CFU/g	< 10 CFU/g	USP
E. coli	Negative	Negative	USP
Salmonella	Negative	Negative	USP

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship