Nervonic acid (NA)

What is Sodium Nervonic acid (NA)? 

Nervonic Acid (NA) is an ω-9 ultra-long-chain monounsaturated fatty acid, chemically known as Cis-15-Tetracosenic Acid. Originally discovered in mammalian nerve tissue, it’s a core component of brain cell membranes and myelin sheaths, constituting 36% of fatty acids in white matter sphingolipids.

 

Applications:

1. Neural Repair & Brain Health

• Myelin Regeneration: Repairs damaged nerve sheaths, improving conduction in conditions like multiple sclerosis and post-stroke deficits.

• Neurodegeneration Delay: Stabilizes brain cell membranes, reduces lipofuscin accumulation, and lowers Alzheimer’s/Parkinson’s risks (>90% efficacy in animal models).

• Cognitive Enhancement: Clinical studies show improved memory, learning ability, and IQ scores with sustained supplementation.

2. Anti-Aging & Metabolic Regulation

• Antioxidant Protection: Activates superoxide dismutase (SOD), reducing oxidative damage to brain cells.

• Glucose/Lipid Control: Enhances insulin sensitivity, lowers LDL, and raises HDL—beneficial for obesity and diabetes.

• Brain Aging Delay: Replenishes white matter deficits and activates dormant neurons, alleviating age-related memory loss and insomnia.

3. Additional Functions

• Infant Neurodevelopment: Natural component of breast milk supporting infant brain/optic nerve development.

• Mood Regulation: Involved in dopamine synthesis; may reduce anxiety/depression (human studies ongoing).

Fuctions:

1. Nutraceutical Ingredient

• Cognitive Health Products: Capsules/tablets for students, professionals, and seniors to enhance memory/focus.

• Neurological Support: Adjunctive formulas for stroke recovery and Parkinson’s management.

• Metabolic Health: Functional foods (e.g., NA-enriched oils) for lipid/glucose regulation.

2. Cosmetic Ingredient

• Anti-Aging Formulations:

  • Serums/Creams: Antioxidant protection against neural skin aging; reduces wrinkles.

  • Eye Creams: Repairs periorbital nerves; diminishes dark circles and fatigue.

• Scalp Treatments:

  • Shampoos/Serums: Nourishes follicular nerve endings; reduces sensitivity and hair loss.

3. Pharmaceutical & Specialty Nutrition

• Neuro-repair Drugs: Injectable/oral treatments for demyelinating diseases .

• Infant Formula: Brain development alternative to DHA (subject to regional infant formula standards).

 💎Nervonic acid (NA) COA generally includes the following test items and standards:

Parameter	Test Method	Specification	Result
Appearance	Visual	White crystalline powder	Compliant
Odor	Olfactory	Odorless	Compliant
Solubility (in water, 25°C)	USP <1231>	≥250 mg/mL	265 mg/mL
pH (1% solution)	EP 2.2.3	6.0-7.5	6.8
Loss on Drying	EP 2.2.32	≤1.0%	0.35%
Specific Rotation [α]²⁵D	EP 2.2.7	+90° to +95°	+92.5°
Parameter	Test Method	Specification	Result
Assay (HPLC)	EP 2.2.29	99.0%-101.0%	99.7%
Related Substances (HPLC)	EP 2.2.29	Total impurities ≤0.5%	0.21%
- Acetoin (major impurity)		≤0.2%	0.08%
Residual Solvents (GC)	ICH Q3C	Class 2 solvents <50ppm	<10ppm
Parameter	Test Method	Limit	Result
Heavy Metals (as Pb)	EP 2.4.8	≤10 ppm	<5 ppm
Arsenic (As)	EP 2.4.2	≤2 ppm	<1 ppm
Cadmium (Cd)	ICP-MS	≤1 ppm	<0.5 ppm
Mercury (Hg)	EP 2.4.8	≤1 ppm	<0.2 ppm
Total Aerobic Count	EP 2.6.12	≤100 CFU/g	<10 CFU/g
Yeast & Mold	EP 2.6.12	≤10 CFU/g	Absent
Pseudomonas aeruginosa	EP 2.6.13	Absent	Absent
Staphylococcus aureus	EP 2.6.13	Absent	Absent

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

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    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

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Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship