Artichoke Extract

What is Artichoke extract? (Artichoke Leaf Extract)

Artichoke extract (Cynara scolymus) is derived from the leaves of this Asteraceae plant, renowned as the “king of vegetables.” Rich in bioactive compounds, its functions, target populations, and precautions are detailed below based on scientific research and clinical evidence.

Applications:

1. Polyphenolic Compounds:

   • Cynarin: Stimulates bile secretion, accelerates fat metabolism and toxin elimination, and supports liver detoxification.

   • Chlorogenic Acid: Potent antioxidant that reduces free radical damage and suppresses inflammation.

   • Luteolin: Inhibits cholesterol synthase (HMG-CoA reductase), lowering LDL (“bad” cholesterol).

2. Dietary Fiber and Prebiotics:

   • Inulin: A water-soluble fiber that promotes the growth of probiotics (e.g., Bifidobacteria) and improves digestive function.

Fuctions:

1. Liver Protection and Detoxification

• Alleviates Fatty Liver: Clinical trials show that daily supplementation of ≥500mg extract for 8 weeks significantly reduces liver enzymes (ALT/AST), particularly in non-alcoholic fatty liver disease (NAFLD) patients.

• Boosts Bile Secretion: Increases bile flow by >40%, accelerating excretion of fat-soluble toxins (e.g., heavy metals, pollutants).

2. Lipid Regulation and Cardiovascular Health

• Lowers Cholesterol: Meta-analyses confirm reductions in total cholesterol (−18%) and LDL (−23%) by inhibiting synthesis and enhancing excretion.

• Blood Pressure Support: After 12 weeks, systolic/diastolic pressure decreases by 2.8–4.7 mmHg, likely due to potassium content (600mg per serving) and improved endothelial function.

3. Digestive System Support

• Relieves Dyspepsia: 640mg extract taken thrice daily for 6 weeks reduces bloating/abdominal pain by 40% and improves quality-of-life scores by 20%.

• Irritable Bowel Syndrome (IBS): Eases alternating diarrhea/constipation by modulating intestinal smooth muscle contraction and exerting anti-inflammatory effects.

4. Other Potential Benefits

• Blood Glucose Control: Animal studies suggest enhanced insulin sensitivity, though human evidence is limited.

• Antioxidant and Anticancer Effects: In vitro studies indicate polyphenols inhibit cancer cell proliferation (e.g., oral squamous carcinoma), but human data is lacking.

• Component	Artichoke Extract	Milk Thistle (Silybum marianum)
  Key Active	Cynarin, Chlorogenic Acid	Silymarin
  Regulatory Status	Dietary supplement (daily support)	Prescription drug (treats liver injury)
  Side Effect Risk	Low (occasional gas/diarrhea)	Potential headaches/GI discomfort
  Primary Use	Fatty liver, high cholesterol, dyspepsia	Hepatitis, cirrhosis (severe liver conditions)

 💎Artichoke Extract COA generally includes the following test items and standards:

Parameter	Specification	Test Method	Result
Cynarin Content	≥1.5%	HPLC	1.62%
Chlorogenic Acid	≥1.4%	HPLC	4.71%
Heavy Metals	≤10 ppm	ICP-MS	<0.1%
Microbial Limits	Absence of pathogens	USP <61>	Compliant
Loss on Drying	≤8.0%	Gravimetric	5.2%
Sulphated Ash	≤8.0%	Gravimetric	4.8%
Batch Number	Unique identifier	—	ACE-2025-500KG

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

---

    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

---

Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

---

Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship