2-(3-(4-hydroxyphenyl)propanamido)benzoic acid

What is 2-(3-(4-hydroxyphenyl)propanamido)benzoic acid?

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid is a class of naturally active ingredients extracted or derived from oats (Avena sativa), and it is a hydrogenated derivative of avenanthramides. Avenanthramides are unique phenolic compounds in oats, while dihydroavenanthramides, after hydrogenation modification of their structures, have more advantages in stability and biological activity, thus being more widely used in skincare and other fields.

Applications:

1. Anti-Inflammatory & Soothing
   → Inhibits pro-inflammatory cytokines (e.g., TNF-α, IL-6), rapidly reducing skin redness, irritation, and itching.
2. Potent Antioxidant
   → Neutralizes free radicals, mitigates oxidative stress, and delays photoaging.
3. Barrier Repair
   → Stimulates filaggrin synthesis, enhances stratum corneum hydration, and repairs compromised skin barriers.
4. Anti-Itch & Anti-Sensitization
   → Blocks neurogenic inflammation pathways (e.g., TRPV1 receptors), suppressing itch signals.

Fuctions:

1. ① Functional Skincare
   • Sensitive Skin Solutions: Soothing serums, eczema/atopic dermatitis treatments, post-procedure recovery creams.
   • Anti-Aging & Sun Care: Antioxidant boosters, sunscreens/makeup primers (reducing UV-induced inflammation).

   ② Medical Applications

   • Burn/wound dressings, adjunctive therapy for steroid-induced dermatitis.

   ③ Scalp & Hair Care

   • Anti-dandruff shampoos, scalp serums (for seborrheic dermatitis/sensitive scalp).

 💎COA generally includes the following test items and standards:

Test Item	Specification Requirements	Test Result	Test Method
Product Name	Dihydroavenanthramide	Dihydroavenanthramide	HPLC
CAS Number	697235-49-7	697235-49-7	HPLC
Molecular Formula	C₁₆H₁₅NO₄	C₁₆H₁₅NO₄	HPLC
Molecular Weight	285.29	285.29	HPLC
Appearance	Off-white powder	Off-white powder	Visual inspection
Purity	≥95%-99%	≥95%-99%	High Performance Liquid Chromatography (HPLC)
Active Ingredient Content	≥5% (for products with 5% content)	≥5%	High Performance Liquid Chromatography (HPLC)
Heavy Metal Content	Lead (Pb) ≤10mg/kg, Arsenic (As) ≤2mg/kg, Mercury (Hg) ≤1mg/kg	Complies with standards	Atomic Absorption Spectroscopy, etc.
Microbiological Indicators	Total bacterial count ≤1000CFU/g, Total mold and yeast count ≤100CFU/g; No detection of fecal coliforms, Staphylococcus aureus, Pseudomonas aeruginosa	Complies with standards	In accordance with the microbiological test methods specified in Safety and Technical Standards for Cosmetics

♻️ FAQ

     Q: Do you support private label customization?
A: Yes! Full-service solutions:

• Formula customization (purity/dosage/form)

• Compliance packaging & labeling

• Global certifications (REACH, FDA, Halal)

---

    Q: How is quality controlled?
A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

---

Q: What if issues arise post-purchase?
A: We guarantee:

• 72h response for quality claims

• Free reformulation support (within 6 months)

• Dedicated account manager

---

Q: Payment & delivery terms?
A:

• Payment: T/T, L/C, PayPal

• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship