Lidocaine hydrochloride Powder

What is Lidocaine hydrochloride Powder?

First, Lidocaine hcl is a local anesthetic and antiarrhythmic drug. Used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including in the thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve conduction block.

Second,Lidocaine hcl is an amide local anesthetic.
With the dose increased, the role or toxicity increased, there is an anti-convulsive effect with sub-poisoning plasma concentration;
Blood concentration of more than 5μg ? ml-1 can occur convulsions.

Third,Lidocaine hcl in low doses can promote outflow of K+ in cardiomyocytes, reduce myocardial autonomy, and has antiarrhythmic effects.

Applications:

Lidocaine hydrochloride has the characteristics of strong penetration, strong dispersion, quick effect, anesthetic efficacy is twice that of procaine, and toxicity is 1. The anesthetic effect can appear 5 minutes after administration, and the anesthetic effect can last for 1 ~ 1.5 hours, 50% longer than procaine. After absorption, it can inhibit the central nervous system, inhibit ventricular automaticity and shorten the refractory period. It can be used to control ventricular tachycardia and treat arrhythmia symptoms such as premature ventricular beats, ventricular tachycardia and ventricular fibrillation. It is effective for cardiac disease or arrhythmia caused by strong cardiac glycosides, but not effective for supraventricular tachycardia. This product has quick action, short duration, and is not effective orally. It is often administered intravenously.

Fuctions:

1. The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action.

2. Epinephrine vasoconstricts arteries, reducing bleeding and also delays the resorption of
lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available
formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine
makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic
procedures.

3. Relative insensitivity to lidocaine is genetic. In hypokalemic sensory overstimulation, relative
insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity
disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons
due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.

4. Lidocaine, along with ethanol,  has also been proven to be effective in
treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

 💎Lidocaine hydrochloride Powder COA generally includes the following test items and standards:

CAS No.	73-78-9
Purity	>99%
Other attributes
Place of Origin	China
Shelf life	2 Years
Other name	Lidocaine hcl
MF	C14H23ClN2O
EINECS No.	200-803-8
Appearance	White Powder & Crystalline Powder
Melting point	80-82ºC
Storage	Inert atmosphere, 2-8ºC
Grade	Medicine Grade
Sample	Available
Package	1KG/Foil Bag 25kg/Drum

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A: Yes! Full-service solutions:

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• Compliance packaging & labeling

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A: 3-Stage QC Protocol:

1. Raw material screening (purity/heavy metals)

2. In-process monitoring

3. Batch COA with traceable LOT

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A: We guarantee:

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• Free reformulation support (within 6 months)

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• Shipping: Global DDP/DAP (MOQ 25kg)

• Stock: 1,000+ metric tons ready-to-ship